I’ve actually thought about doing this multiple times. Not Twitter actually, but Facebook for now. The only thing that stops me is some university groups that we only have on Facebook that are useful sometimes. However, I already uninstalled it from my phone. Sometimes I wanna show someone something and then I think “I don’t have FB installed”, but it doesn’t matter anyway. Usually it’s not something that important.
Or if you don't know what a response is, you can always write a webmention comment (you don't need to know what that is).